报告题目：动物重要病原的可视化及互作机制研究

报告人： 张付贤

报告时间：2021年7月3日 下午3:00

报告地点：5教807 会议室

教育经历

2009-2014，中国科学院大学，生物化学与分子生物学，博士
2006-2009，吉林大学，预防兽医，硕士
2001-2006，河南科技学院，动物科学，学士

研究方向

研究方向为人兽共患病病原微生物致病机理及疫病的防控。主要研究内容为致病病原病原与宿主、环境互作的分子机制、宿主免疫应答及信号通路、宿主嗜性与共感染、跨种感染及传播机制；疫病快速检测技术、新型生物制品与药物的研究。

代表性论文

1.Chuntong Bao, Hexiang Jiang, Rining Zhu, Baijun Liu, Jiameng Xiao, Ziheng Li, Peiru Chen, Paul R Langford, Fuxian Zhang*, Liancheng Lei*. Differences in pig respiratory tract and peripheral blood immune responses to Actinobacillus pleuropneumoniae. Vet Microbiol. 2020;247:108755
2.Fuxian Zhang, Hong Guo, Qingxiu Chen, Zheng Ruan, Qin Fang*. Endosomes and Microtubles are Required for Productive Infection in Aquareovirus. Virol Sin. 2020;35(2):200-211.
3.Xurong Wang#, Fuxian Zhang#, Rui Su, Xiaowu Li, Wenyuan Chen, Qingxiu Chen, Tao Yang, Jiawei Wang, Hongrong Liu*, Qin Fang*, and Lingpeng Cheng*. Structure of RNA polymerase complexand genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly. Proceedings of the NationalAcademy of Sciences (PNAS), June 25, 2018. 20180388.
4.Pan Yangang#; Zhang Fuxian#; Zhang Liuyang; Liu Shuheng; Cai Mingjun; Shan Yuping*; Wang Xianqiao*; Wang Hanzhong*; Wang Hongda*; The Process of Wrapping Virus Revealed by a Force Tracing Technique and Simulations , Advanced Science, 2017, 4(9): 0-1600489.
5.Fuxian Zhang, Hong Guo, Jie Zhang, Qingxiu Chen, Fang Qin*. Identification of the caveolae/raft-mediated endocytosis as the primary entry pathway for aquareovirus, Virology, 2018, 513(2018): 195-207.
6.Jie Zhang, Hong Guo, Fuxian Zhang, Qingxiu Chen, Mingxian Chang, Qin Fang*. NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A. Virology. 2019;529:216-25.