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团队队伍

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黄廷华副教授动物科学系系主任

所在系所: 动物科学系

办公电话: 13397215027

通讯地址: 银河国际网站4556西校区农学院

电子邮件: thua45@yangtzeu.edu.cn

个人主页: http://www.thua45.cn

教育背景

2004年6月毕业于华中农业大学动物科学专业，同年9月考入华中农业大学动物遗传育种与繁殖教育部重点实验室攻读硕士学位。2009年6月获得动物遗传育种博士学位。
工作经历

2013年7月至今在银河国际网站4556从事教学科研工作。
出访及挂职经历

2009年6月至2013年6在美国爱荷华州立大学农业与生命科学学院动物科学系从事猪沙门氏菌感染相关的研究工作。
研究方向

动物遗传、病理学与生物信息学
科研项目

1).国家自然科学基金，结合位点富集分析法解析miRNA参与猪抗沙门氏菌感染的遗传调控机制，2015-2017，24万 2).教育部留学归国科研启动基金，MS4A8B基因参与猪抗沙门氏菌感染的作用机制，2015-2016，3万 3).长江青年人才基金，MiR-143调节沙门氏菌感染及其作用机制，2015-2018，5万
代表性论文专著

1. Huang, T., M. Yang, K. Dong, M. Xu, J. Liu, Z. Chen, S. Zhu, W. Chen, J. Yin, K. Jin, Y. Deng, Z. Guan, X. Huang, J. Yang, R. Han and M. Yao (2020). "A transcriptional landscape of 28 porcine tissues obtained by super deepSAGE sequencing." BMC Genomics 21(1): 229. 2. Huang, T., X. Huang, B. Shi, F. Wang, W. Feng and M. Yao (2018). "Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs." Veterinery Research 49: 121. 3. Huang, T., X. Huang, B. Shi and M. Yao (2019). "GEREDB: Gene expression regulation database curated by mining abstracts from literature." J BioinformComputBiol 17(4): 1950024. 4. Huang, T., X. Huang and M. Yao (2019). "Min3: Predict microRNA target gene using an improved binding-site representation method and support vector machine." J BioinformComputBiol 17(5): 1950032. 5. Tinghua Huang#, Xiali Huang, Bomei Shi, Xiongyan Liang, Jingbo Luo, Min Yao*, Relationship between MS4A8 expression, its variants, and the immune response in a porcine model of Salmonella, Canadian Journal of Animal Science, 2018 (Accepted) 6. Tinghua Huang#,Xiali Huang, Min Yao*, miR-143 inhibits intracellular salmonella growth by targeting ATP6V1A in macrophage cells in pig, Res Vet Sci, 2018, 117(1): 138~143 7. Min Yao#, Weihua Gao, Hengxun Tao, Jun Yang, Tinghua Huang*, The regulation effects of danofloxacin on pig immune stress induced by LPS. Research Veterinary Science, 2017, 110: 65-71 (IF: 1.5) 8. Min Yao#, Qinghua Wu, Juan Li, Tinghua Huang*, K-walks: clustering gene-expression data using a K-means clustering algorithm optimised by random walks. International Journal of Data Mining and Bioinformatics, 2016, 16(2): 121-140 (IF:0.5). 9. Min Yao#, Weihua Gao, Jun Yang, Xiongyan Liang, Jingbo Luo, Tinghua Huang*, The regulation roles of miR-125b, miR-221 and miR-27b in porcine Salmonella infection signaling pathway. Biosci Rep, 2016, 36(4): e00375 (IF:2.2) 10. Min Yao#, Weihua Gao, Hengxun Tao, Jun Yang, Guoping Liu, Tinghua Huang*, Regulation signature of miR-143 and miR-26 in porcine Salmonella infection identified by binding site enrichment analysis. Mol Genet Genomics, 2015, 10 (1): 1-14 (IF: 2.7). 11. Huang TH, Yang J, Liu GP, Jin W, Liu Z, Zhao SH, and Yao M, Quantification of Mature MicroRNAs Using Pincer Probes and Real-Time PCR Amplification. PLoS One, 2015. 12. Huang TH, Uthe JJ, Bearson SM, Demirkale CY, Nettleton D, Knetter S, Christian C, Ramer-Tait AE, Wannemuehler MJ, and Tuggle CK, Distinct peripheral blood RNA responses to Salmonella in pigs differing in Salmonella shedding levels: intersection of IFNG, TLR and miRNA pathways. PLoS One, 2011. 6(12): p. e28768. 13. Huang TH, Zhu MJ, Li XY, and Zhao SH, Discovery of porcine microRNAs and profiling from skeletal muscle tissues during development. PLoS One, 2008. 3(9): p. e3225. （引用频次：89，Google Scholar） 14. Huang TH, Fan B, Rothschild MF, Hu ZL, Li K, and Zhao SH, MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans. BMC Bioinformatics, 2007. 8: p. 341. （引用频次：64，Google Scholar） 15. Cao J, Huang TH, Li X, and Zhao S, Interactome mapping reveals important pathways in skeletal muscle development of pigs. Int J Mol Sci, 2014. 15(12): p. 21788-802. 16. Li Z, Lan X, Guo W, Sun J, Huang Y, Wang J, Huang TH, Lei C, Fang X, and Chen H, Comparative transcriptome profiling of dairy goat microRNAs from dry period and peak lactation mammary gland tissues. PLoS One, 2012. 7(12): p. e52388. 17. Xie SS, Huang TH, Shen Y, Li XY, Zhang XX, Zhu MJ, Qin HY, and Zhao SH, Identification and characterization of microRNAs from porcine skeletal muscle. Anim Genet, 2010. 41(2): p. 179-90. 18. Tuggle CK, Bearson SM, Uthe JJ, Huang TH, Couture OP, Wang YF, Kuhar D, Lunney JK, and Honavar V, Methods for transcriptomic analyses of the porcine host immune response: application to Salmonella infection using microarrays. Vet Immunol Immunopathol, 2010. 138(4): p. 280-91. 19. Zhou QY, Fang MD, Huang TH, Li CC, Yu M, and Zhao SH, Detection of differentially expressed genes between Erhualian and Large White placentas on day 75 and 90 of gestation. BMC Genomics, 2009. 10: p. 337. 20. Feng Y, Huang TH, Fan B, and Zhao SH, Mapping of six miRNAs expressed in porcine skeletal muscle. Anim Genet, 2008. 39(1): p. 91-2. 21.Knetter SM, Bearson SM, TinghuaHuang, Kurkiewicz D, Schroyen M, Nettleton D, Berman D, Cohen V, Lunney JK, Ramer-Tait AE, Wannemuehler MJ, and Tuggle CK*, Salmonella enterica serovar Typhimurium-infected pigs with different shedding levels exhibit distinct clinical, peripheral cytokine and transcriptomic immune response phenotypes. InnateImmun, 2015. 21(3): p. 227-41. 22. 黄廷华, 樊斌, 徐三平, 李奎, 刘榜, 通城猪保种与利用信息管理系统的开发. 中国畜牧杂志, 2006. 42(3): p. 50-51.
教学工作

主要承担了本科生的《猪生产学》、《分子生物学》、《专业英语》等课程的教学。科研方面，主要从事猪沙门氏菌感染的遗传调控机理研究。截止目前，以第一作者（或通讯作者）在《Veterinary Research》、《BMC Genomics》、《BMC Bioinformatics》、《Journal of Bioinformatics and Computational Biology》等杂志上发表SCI论文14篇，论文累计引用频次380多次，是《BMC Genomics》、《Animal Genetics》、《Current bioinformatics》等杂志特约审稿人。
软件版权登记及专利

1). miRfindermiRNA前体预测软件（开源） 2). K-walks聚类分析软件 3). GEREDB数据库
学术兼职
荣誉奖励

银河国际网站4556“长江青年人才”

教育背景

工作经历

出访及挂职经历

研究方向

科研项目

代表性论文专著

教学工作

软件版权登记及专利

学术兼职

荣誉奖励